الفهرس | Only 14 pages are availabe for public view |
Abstract Inflammatory bowel disease (IBD) is a generic term used to describe two idiopathic disorders that are associated with gastrointestinal inflammation: Crohn’s disease (CD) and ulcerative colitis (UC). These disorders need to be distinguished from other conditions that may display similar clinical and laboratory findings, such as infection, allergy, and neoplasm. The ultimate definition of UC and CD rests with the location and characteristics of inflammation within the gastrointestinal tract. In UC, a relatively homogeneous inflammatory process is confined to the mucosa, which starts in the rectum and involves a variable extent of colon proximally, while CD may involve any portion of the alimentary tract, from mouth to anus. Mucosal inflammation in CD may be generalized or patchy and may extend gradually into the submucosa, muscularis, and serosa. This transmural inflammation can result in further intestinal complications |