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Abstract Human stem cells research holds enormous potential for contributing to our understanding of fundamental human biology. Although it is not possible to predict the outcomes from basic research, such studies will offer the possibility for treatments and ultimately for cures for many diseases for which adequate therapies do not exist (Audrey et al., 1999). Key questions regarding adult stem cells are: (1) Their identity, (2)Their tissue source of origin, (3)Their ability to form other cell or tissue types, and (4)The mechanisms behind such changes in differentiation and effects on tissues and organs (Ramer et al., 2000). Once thought impossible, repairing the damaged spinal cord is now entering the realm of feasibility. Tow important concepts are shortening the path to successful restoration: 1) It is not necessary to cure a spinal cord injury, and 2) A disproportional return of function can result from a small degree of regeneration. Substantial loss of spinal cord tissue, particularly gray matter, does not preclude near normal long tract function (McDonald et al., 2004). |