الفهرس 
REVIEW OF LITERATUREOnly 14 pages are availabe for public view
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Abstract
The technique known as FISH, relies on the unique ability of a portion of single stranded DNA, known as a probe to hybridise with its complementary target sequence wherever it is located in the genome. The probe is conjugated with a fluorescent label allowing it to be visualised under ultraviolet light.
We have demonstrated the contribution of FISH in mapping 16q22.1 as refined LOH mapping in primary sporadic breast tumour has shown allelic imbalance of SRO2 located at this region.