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العنوان
Plasma carnitine status of children with chronic liver disease and cirrhosis/
الناشر
Ain Shams uni. medicine. Pediatric
المؤلف
Dalia Mahmod،Khattab
هيئة الاعداد
مشرف / Abd El-Megeed، . Abeer Ibrahi
مشرف / Hassan، . Mona Rashad
مشرف / El Kaban، Zeinab Anwa
باحث / Dalia Mahmod،Khattab
تاريخ النشر
2004
عدد الصفحات
130p.
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب الباطني
تاريخ الإجازة
1/1/2004
مكان الإجازة
جامعة عين شمس - كلية الطب - Pediatric
الفهرس
Only 14 pages are availabe for public view

from 95

from 95

Abstract

Carnitine is naturally occurring hydrophilic amine acid derivative, produced endogenously in the liver and kidney and derived from meat and dairy products in the diet(Scaglia,2002).
Carnitine is essential for long chain fatty acid oxidation . Fatty acids cannot penetrate the inner mitochondrial matrix and enter the mitochondrial membrane to undergo oxidation unless they transported across the inner membrane by a carrier process involving carnitine (Fuller and Hoppel,1983).
As The synthesis of Carnitine is performed in the liver ,subnormal plasma carnitine concentrations are expected in patients with liver disease specially cirrhotic patients and therefor causing secondary carnitine deficiency (Selimoglu et al.,2001).