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Abstract The WHO estimates 170 million individuals worldwide are infected with HCV. However, the prevalence of HCV infection varies throughout the world. For example, Frank, et al. in (2000), reported that Egypt has the highest number of reported infections, largely attributed to the use of contaminated parenteral antischistosomal therapy. This has led to a mean prevalence of HCV antibodies in persons in Egypt of 22%. While El Zayadi, et al. (1997), revealed that HCV has prevalence rates of over 20%, especially in patients suffering from schistosmiasis and treated with injection. HCV is considered the most common etiology of chronic liver disease in Egypt, where the seroprevalence is 10-folds greater than that in USA and Europe (Stickland, et al., 2002). Ministry of health and population, Preventive Sector, Epidemiology and Surveillance stated that 7% of all Egyptian deaths annually are associated with either cirrhosis or hepatocellular carcinoma, and 75-85% of persons with these conditions have either chronic hepatitis C virus or chronic hepatitis B virus as a contributing cause (National guidelines for communicable diseases surveillance, Cairo, 2001). |