الفهرس 
Introduction and Aim of the workOnly 14 pages are availabe for public view
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Abstract
This study included 60 patients (42 male and 18 females) with a mean age 46.77 years ranging from 14 to 81 years old who fulfilled the clinical criteria and the first three electrodiagnostic criteria of the EFNS/PNS guidelines on management of CIDP (Hughes RA,2006). The study was conducted in Ain Shams University Hospitals.
The study was designed aiming to:
1. Focus on clinical presentations, neurological disabilities and associated concurrent illnesses among CIDP Egyptian patients.
2. Determine the effectiveness of oral prednisone, plasma exchange and intravenous immunoglobulins in comparison to each other as available therapeutic agents.
3. To investigate the role of TNFα and MMP9 as markers for the diagnosis of CIDP patients which may be of help in the planning for future new models of treatment .
All patients were submitted to:
1. Full general and neurological history and examination.
2. Neuropathy Impairment Score (NIS) and Modified Rankin Scale (MRS) were performed for each patient before the start of treatment.
3. Laboratory investigations including routine immunological tests and serum level of TNFα (in all the patients and 20 controls).
4. CSF analysis.
5. Neurophysiological assessment: electromyography and nerve conduction studies.
6. Sural nerve biopsy for electron microscopy study and immunohistochemical assessment for MMP9 expression.