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العنوان
MOLECULAR STUDY OF CMV IN POLYTRANSFUSED AND IMMUNOCOMPROMISED CHILDREN/
الناشر
Ain Shams uni. Medicine. Pediatrics
المؤلف
Emara، Doaa Hassan
هيئة الاعداد
مشرف / El-Sayed، Manal Hamdy
مشرف / El-Beblawy، Nagham M.S
مشرف / Draz، Nehal Ibrahim
باحث / Emara، Doaa Hassan
تاريخ النشر
2004
عدد الصفحات
120p.
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب الباطني
تاريخ الإجازة
1/1/2004
مكان الإجازة
جامعة عين شمس - كلية الطب - Pediatrics
الفهرس
Only 14 pages are availabe for public view

from 145

from 145

Abstract

Viral infection is a well-known risk of blood product transfusion and much work has been devoted for the detection of such well-known pathogen as human immunodeficiency virus (HIV) and hepatitis viruses in blood donors. Cytomegalovirus (CMV) is found in a much larger percentage of donor units than other viruses but will cause disease in only a minority of recipients (Gunter, 1995).
Cytomegalovirus is a double stranded DNA virus, which can be transmitted by blood transfusion and belongs to the Herpesviridae family (Drago et al., 2000).
Human CMV remains an important cause of illness in immunocompromized individuals and the most common viral cause of congenital malformation (Rawlinson, 1999).
It was previously reported that the use of PCR in detecting CMV DNA in serum enables the detection of CMV viremia, which has not been possible with other methods (Matsumage et al., 1999).