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Abstract
In the present investigation, eighty immature channel catfish with average weight 100 gm ±5 were used. The fish were kept in a glass aquaria one week before the beginning of the experiment for acclimation period. The water temperature about 22-23°c and pH level kept at 7.6±0.4. dechlorinated tap water was supplied with oxygen by air pump. The fish were fed by commercial pelleted ration at 3% of body weight. The fish were divided into 7 groups. The first group reserved as a control.The second and third groups exposed to Deltamethrin in a concentration 0.5µg /L and0.75 µg/ L for one week. The fourth group exposed to mercuric chloride in a concentration of 140 µg/ L for one week. The fifth group exposed to both Deltamethrin and mercuric chloride in a concentration 0.75 and 140 µg/ L respectively. The results revealed that ALT, AST, urea, creatinine and blood glucose were significantly increased while total protein, albumin were significantly decreased, GSH and catalase activity of (liver, Kidneys and gills) also were significantly decreased in groups exposed to Deltamethrin and / or mercuric chloride when compared with control group while ALT, AST, urea, creatinine and blood glucose were significantly decreased while total protein, albumin were significantly increased, GSH and catalase activity of (liver, Kidneys and gills) also were significantly increased in groups exposed to vitamin E or group exposed to copper when compared with mixed polluted group and Deltamethrin group respectively.