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Abstract This study was conducted to throw the light on the effects of Clarias lazera exposure to the herbicide thiobencarb in concentrations of (1.0 & 2.0 pp m) on liver and kidney functions furthermore, studying the effect of thiobencarb at both concentrations on total proteins, albumin, globulins, glucose, cholesterol, triglycerides and cholinesterase enzyme activities. As well as its effect on some serum electrolytes (calcium, sodium and potassium). The histopathological changes were also recorded. The results are summarized as foiIows: * Biochemical effects: 1- Liver function tests: The exposure of catfish (Clariaz lazera) to both concentrations of thiobencarb resulted in a significant increase in serum levels of AST, ALT and ALP along the course of the experiment (14 days). whereas the activities of these enzymes were decreased during the recovery period (7 days). 2- Serum total proteins, albumin & globulins: Serum total proteins, albumin and globulins showed a marked increase during the entire period of exposure, then returned to their normal limits during recovery period. |