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Abstract
Serum concentration of PTH are often elevated in chronic renal
failure, resulting in hyperparathyroid bone disease or osteitis fibrosa.
The two major factors responsible development of secondary
hyperparathyroidism are phosphorus retention and diminished 1,25
(OH)2D3 .. The two active vitamin D sterols, calcitriol and ex calcidol
are effective in suppressing intact parathyroid hormone and treatment
of secondary hyperparathyroidism in chronic renal failure.
This study was done to determine senlm 1,25 (OH)2D3 in
chronic renal failure patients under haemodialysis therapy in a trial to
clarify the effect of its oral therapy in the control of secondary
hyperparathyroidism.
This study was conducted on 40 patients suffering from chronic
renal failure, under haemodialysis and 10 control subjects. Patients