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العنوان
Design And Synthesis Of Some Carboxylic Acid Derivatives As Potential Anti-Inflammatory Agents /
المؤلف
El-Sayed,Azza El-Sayed Ismail Ismail.
هيئة الاعداد
مشرف / السباعى ابراهيم
مشرف / على ابو الفضل هزاع
مشرف / منير خليل
مشرف / احمد حسن
الموضوع
Pharmaceutical Chemistry.
تاريخ النشر
2005.
عدد الصفحات
124 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الصيدلة ، علم السموم والصيدلانيات
تاريخ الإجازة
1/1/2005
مكان الإجازة
جامعة الاسكندريه - كلية الصيدلة - Pharmaceutical Chemistry
الفهرس
Only 14 pages are availabe for public view

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Abstract

It is well documented that derivatives of quinazolin-4(3H)-one alone or fused with other heterocycles possess a broad spectrum of biological activity especially anti-inflammatory activity.
Based on the above-mentioned information, a series of new quinazolin4(3H)-ones bearing various heterocyclic moieties were synthesized in this thesis.
Selected members of these compounds were screened for their anti- inflammatory activity.
The present thesis is subdivided into the following chapters:
Chapter I: Introduction:This chapter covers a brief survey on the recent researches on
biologically active quinazolin-4(3H)-ones possessing anti-microbial, anticonvulsant, anti-histaminic, hypoglycemic, cardiovascular, anthelmintic, anti-cancer and anti-inflammatory activities.
Chapter II : Research Objectives:It deals with the rationale upon which the target compounds have
been designed.
Chapter III : Discussion:In this part, the basic concepts of various methods adopted for the
synthesis of the designed compounds are presented.