الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Polycystic ovary syndrome PCOS is characterized by chronic anovulation and hyperandrogenism. Women with PCOS are at an increased risk for infertility, preclamsia, early pregnancy loss, and endometrial cancer. Moreover, because of association of PCOS with insulin resistance, evidence suggests that women with PCOS are at an increased risk for developing type 2 diabetes, dyslipidemia, hypertension and heart disease. (193,194).
Ghrelin was discovered as the peptide hormone that potentially stimulates release of growth hormone from the anterior pituitary. It has significant effects on appetite and energy balance. The predominant source of ghrelin is epithelial cells in the stomach(43).
The aim of the work in the present study was to evaluate ghrelin level in PCOS patients who were diabetic and the non diabetes groups in comparison to normal control female subjects.
The present study included 60 female subjects selected from Shatupy University Hospital as following: 25 female subjects had PCOS without diabetes mellitus, 25 female subjects had PCOS with type 2 diabetes mellitus and 10 female subjects were healthy control. Pregnant females were excluded