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العنوان
Non Invasive Markers of Liver Fibrosis in Patients with HCV Infection :
الناشر
Hend Mohammed Moness Aly ,
المؤلف
Aly, Hend Mohammed Moness
هيئة الاعداد
باحث / Hend Mohammed Moness Aly
مشرف / Ahmed Abdel Semie EL-Sherif
مشرف / Ayman Gamil Gohbrial
مشرف / Hanan Mustafa Kamel
الموضوع
Clinical Pathology - Liver Fibrosis - HCV Infection -
تاريخ النشر
2007 .
عدد الصفحات
120 p.:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب (متفرقات)
تاريخ الإجازة
1/1/2007
مكان الإجازة
جامعة المنيا - كلية الطب - Department of Clinical Pathology
الفهرس
Only 14 pages are availabe for public view

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Abstract

The Aim of the Work
The aim of this study is to evaluate the relationship between biochemical markers of liver fibrosis, platelets and coagulation parameters: prothrombin time and factor VII
Results:
In comparison of each parameter of laboratory investigation between both groups .It was found that there was significant difference between both groups in absolute neutrophil count ( p 0.019), platelets count (p 0.00017 ) , AST( p 0.00064 ) , ALT ( p 0.0081), GGT( p 0.000001 ) , total bilirubin ( p 0.03114 ) , direct bilirubin( p 0.0009) , prothrombin time( p 0.000046) , prothrombin conc.( p 0.000003) , factor VII conc.( p 0.00061 ) and haptoglobin ( p 0. 000088 ) .
In addition there was strong correlation between:
1) Total bilirubin and factor VII.
2)Haptoglobin and platelet count.
3) Haptoglobin and prothrombin conc.
4) Haptoglobin and factor VII conc.
5)Apolipoprotein A1 and prothrombin conc.
6) Apolipoprotein A1 and factor VII conc.
On the other hand there was no significant correlation between ALT: platelets, p. conc., factor VII conc. and absolute neutrophil count.
No significant correlation between Total bilirubin: platelets, p. conc. and absolute neutrophil count.
No significant correlation between GGT: platelets, p. conc., factor VII conc. and absolute neutrophil count.
No significant correlation between α2 macroglobulin: platelets, p. conc., factor VII conc. and absolute neutrophil count.
No significant correlation between Haptoglobin and absolute neutrophil count.
No significant correlation between Apolipoprotein A1: platelets and absolute neutrophil count.