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Abstract
The aim of this study was to identify and study congenital brain lesions with presentation of their diagnostic imaging features by CT and MRI. Initial review of the embryology of the brain, stages of brain development, anatomy of the brain, normal CT and MRI sectional anatomy of the brain and classi fication of congenital brain lesions and the CT and MRI appearance were thoroughly evaluated. finy patients with congenital brain lesions were included III this study. These patients were 24 males and 26 females.
;\1\ patients were subjected to axial CT scans and axial ami sagittal Tl weighted images and axial ’1’2 weighted images.
The most cOlllmon antenatal risk factor for the development of congenital brain mal formations was found to be consangumeous marrIages. On the other hand, seizures and delayed milestones were the commonest presenting symptoms. The patients \\ere classi fied according to the time of insult of these congenital lesions in prenatal life into 5 groups. Dysgenesis of the corpus callosum was the most commonly encountered lesion among patients of the present study as it was present In I G patients. Each of meningoencephaloceles ami i\rnold-Chiari malformation was present in 7 cases. Moreover, holoprosencephaly and Dandy-Walker syndrome were present in 5 cases. Next in frequency was neuronal heterotopias and hydrancephaly, each was present in 4 cases. Each of cerebellar hypoplasia, cran iosynostosis and \ issencephal y was present \n 3 cases. Hemimegalencepha\y, tuberous sclerosis, aneurysm of veIn of Galen, polymicrogyria and schizencephaly, each was present in only 2 cases. finally, Sturge-Weber syndrome was present in one case. Clinical and radiological imaging features for each disease were demonstrated in view of other available published data.