الفهرس | Only 14 pages are availabe for public view |
Abstract Aim of the work To assess changes in heart rate variability, cardiac arrhythmia as well as to assess whether QT dispersion is increased in patients with acute cerebral stroke and whether these changes are related to lesion type, size and or localization. Results We reviewed 12 lead ECG tracings of patients and control subjects. We found that: 1- QTD increased in patients with acute stroke whether ischemic or hemorrhagic compared to control subjects. 2- QTD was higher in hemorrhagic stroke compared with thrombotic stroke. 3- QTD was higher in patients with stroke involving the insular cortex than cases without such involvement. 4- QTD has positive significant correlation with NIH score at discharge and modified Rankin Scale. 5- QTD has significant negative correlation with patient’s improvement as judged by NIH change and Barthel index change denoting that higher QTD may predict less improvement. Moreover QTD was significantly higher in patients who died during hospitalization for acute stroke compared to those who survived. Also analysis of data of 24 hours Holter-monitoring revealed that: 1- LF in nu. And LF/HF ratio were higher in patients of stroke whether ischemic or hemorrhagic compared to control subjects denoting that there is higher sympathetic predominance during acute stroke, the factor that enhances arrhythmia, increase risk of sudden death. 2- Both LF components in nu. And LF/HF ratio had a significant negative correlation with patient’s improvement as judged by change in NIH score and change in the Barthel index from admission to discharge, denoting that higher sympathetic predominance on admission may predict less improvement during the subsequent course following acute stroke. |