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العنوان
Synthesis Of Novel Quinazolone Derivatives As Potential Antimicrobial Agents /
المؤلف
Abdel-Azim, Mohamed Ashraf Gaber.
هيئة الاعداد
مشرف / احمد فرغلى
مشرف / محسن عمر
مشرف / محمد خليل
باحث / محمد اشرف جابر
الموضوع
Pharmaceutical Chemistry.
تاريخ النشر
1984.
عدد الصفحات
167 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الصيدلة ، علم السموم والصيدلانيات
تاريخ الإجازة
1/1/1984
مكان الإجازة
جامعة الاسكندريه - كلية الصيدلة - Pharmaceutical Chemistry
الفهرس
Only 14 pages are availabe for public view

from 180

from 180

Abstract

Part I:
As a part of an extensive program aimed at studying the effect of structure modification on the antimicrobial activity of compounds containing thiocarba— moyl functions, tiziazoline and thiazolidinone ring systems, sixty nine new thioureas, thiosemicarbazones, thiazolines, and thiazolidinones derived from 4(3H)— quinazolinone were synthesized. The synthetic as well as the biological results are presented in three main parts as follows:
Deals with. the synthesis of ten new 2—metbyl—3-. substituted thiocarbaiaoylamino—4(3H)—quinazolinones (lila_i) and their cyolization into the corresponding 2—methyl—3—(3—subst itut ed—4—phenyl—2 , 3—dihydrothiazol—
—2—ylideneamino)—4(3R)—quinazolinones (IVa_j) and 2—metbyl—3—(3—subst ituted—4—oxotbiazolidin—2—ylidene— amino)—4 (3H)—quinazolinones (VIaj)•