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Abstract Five agents; benzoic acid, bronopol, phenol, phenyl— mercuric acetate arid propyl paraben, were tested for their fungistatic activity against two moulds; Aspergillus niger and Penici11iuz chrysoenum, a well as two yeasts; Candida albicans and Saccharomvces cerevisiae. Among these agents, phenylrnercuric acetate was the most effective, this s followed by propyl paraben and bronopol, while the least effective agents were benzoic acid and phenol. The minimum inhibitory concentration (MIC) depended partly on the nature of the medium used for the test. with benzoic acid, propyl paraben, bronopol, and phenylmercuric acetate, higher NIC values were obtained in Sabouraud medium than in Czapek—malt when using the two yeasts. In contrast, Czapek—malt gave higher MIC values against .chrvsogenum. With .niger, however, both media gave nearly the same MIC values, except with propyl paraben where higher values were obtained with Czapek—m3lt. In case of phenol, its fungistatic concentration, however, did not vary by altering the medium. Regardless of the type of medium used, the yeasts were found to be more sensitive than moulds towards phenylmercuric acetate. With phenol, uioulds were, however, more sensitive than yeasts. On the other hand, the sensitivity of the tested fungi towards bronopol, propyl paraben and benzoic acd varied according to the medium used. Among the tested fungi, k.niger |