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العنوان
Studies On The Antifuncal Activity Of Some Preservative/
المؤلف
Soliman, Gaber Sadek Homaydan.
هيئة الاعداد
مشرف / عبدالغنى السيد الخولى
مشرف / رمزى تادرس يوسف
باحث / جابر صديق سليمان
مناقش / احمد محمد خليل
الموضوع
Pharmaceutical microbiology.
تاريخ النشر
1974 .
عدد الصفحات
188 p.:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الصيدلة ، علم السموم والصيدلانيات
تاريخ الإجازة
1/1/1974
مكان الإجازة
جامعة الاسكندريه - كلية الصيدلة - Pharmaceutical Microbiology
الفهرس
Only 14 pages are availabe for public view

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from 193

Abstract

Five agents; benzoic acid, bronopol, phenol, phenyl— mercuric acetate arid propyl paraben, were tested for their fungistatic activity against two moulds; Aspergillus niger and Penici11iuz chrysoenum, a well as two yeasts; Candida albicans and Saccharomvces cerevisiae. Among these agents, phenylrnercuric acetate was the most effective, this s followed by propyl paraben and bronopol, while the least effective agents were benzoic acid and phenol. The minimum inhibitory concentration (MIC) depended partly on the nature of the medium used for the test. with benzoic acid, propyl paraben, bronopol, and phenylmercuric acetate, higher NIC values were obtained in Sabouraud medium than in Czapek—malt when using the two yeasts. In contrast, Czapek—malt gave higher MIC values against .chrvsogenum. With .niger, however, both media gave nearly the same MIC values, except with propyl paraben where higher values were obtained with Czapek—m3lt. In case of phenol, its fungistatic concentration, however, did not vary by altering the medium.
Regardless of the type of medium used, the yeasts were found to be more sensitive than moulds towards phenylmercuric acetate. With phenol, uioulds were, however, more sensitive than yeasts. On the other hand, the sensitivity of the tested
fungi towards bronopol, propyl paraben and benzoic acd varied
according to the medium used. Among the tested fungi, k.niger