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Abstract
The aim of this study is assessing the value of unnarv
calcium/creatinine ratio in a random voided urine sample in assessing the
degree of calcium excretion in nephrotic children as an index: for
hypercalciuria as well as the abdominal ultrasonography in assessing the
degree of nephrocalcinosis.
The study was conducted on 70 patients; 35males and 35 females
and 30 healthy controls; 15 males and 15 females who were subjected to:
- Complete blood count.
- Serum albumin and cholesterol level.
- Serum calcium, phosphorus and alkaline phosphatase.
- Assessment of calcium and creatinine in a spot urine sample obtained
randomly.
- Abdominal ultrasonography.
Subjects were subdivided into 3 main groups:
Group A: 30 patients steroid resistant; 12 males and 18 females.
Group B: 40 patients steroid sensitive 24 males and 16 females.
Group C: 30 healthy controls; 15 males and 15 females.
In our study, we exclude patients who receive immunosuppressive
drugs. Also, we exclude patients with other systemic diseases as
musculoskeletal disease, liver disease and chomic renal failure.
from our study, we can conclude that:
Hypercalciuria in nephrotic children is mainly due to long duration of
furosemide and steroid therapy and it is transient process which may