الفهرس 
Introduction and aim of the workOnly 14 pages are availabe for public view
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Abstract
The aim of the work:
1- Detection of the serum level of hepatocyte growth factor (HGF) in patients with chronic liver diseases.
2- Detection of the serum level interleukin 1 beta (IL-1 β) in those patients.
3- To study the possible correlation of the serum levels of HGF & IL-1 β with each others and with the activity and prognosis of chronic liver diseases.
Conclusions:
1- Our study revealed that serum levels of HGF were higher in patients with chronic liver diseases than controls, with the highest level in patients with CC because it is expressed on and secreted from malignant cells. Followed by liver cirrhosis due to impairment of its excretion, followed by chronic hepatitis due to increase the necro-inflammatory activity.
2- High serum levels of HGF in C virus related chronic liver diseases may predict a carcinogenic state and HGF may be used as a tumor marker.
3- The mean serum levels of IL-1 β were higher in patients with chronic liver diseases than controls, with the highest levels in patients with HCC, followed by liver cirrhosis, followed by chronic hepatitis. Indicating that IL-1 β plays a role in inflammation and hence prognosis of liver diseases.
4- There was a significant positive correlation between serum levels of HGF and IL-1 β with each other, and with the activity and severity of liver diseases.
5- Bilharziasis and parenteral anti bilharzial drugs were the most common risk factors of HCV infection.