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Abstract
This work aims to make a review of the literature about the effect of cigarette smoke as a major health problem on male and female reproductive systems. Cigarette smoking is a serious health problem of our society. According to World Health Organization approximately one third of the world’s population above 15 years of age smokes. It was reported that cigarette smoke is a cell mutagen and carcinogen and it may adversely affect fertility.
Tobacco smoke also contains some of the most toxic chemicals. Men smokers inhale directly and absorb the following substances: nicotine, carbon monoxide, nitrogen oxide, benzo[a]pyrene, mutagenic pyrolysis-derived compounds and cadmium most of them are known to be mutagens or carcinogens which may directly affect male and female reproductive systems.