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العنوان
Possible Interactions Between Alpha-2 Acting Drugs and Some Anxiolytics /
الناشر
Entesar Farghalli Amin,
المؤلف
Amin, Entesar Farghalli.
هيئة الاعداد
باحث / Entesar Farghalli Amin
مشرف / Mohamed Montaser A. Khalifa
الموضوع
Pharmacology Alpha-2 Alpha-2 Acting Drugs Anxiolytics
تاريخ النشر
1996 .
عدد الصفحات
97p.
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
جراحة
تاريخ الإجازة
1/1/1996
مكان الإجازة
جامعة المنيا - كلية الطب - Pharmacology
الفهرس
Only 14 pages are availabe for public view

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from 118

Abstract

In conclusion, it is evident that yohimbine increases the spontaneous locomotor activity of rats while diazepam inhibit it. Moreover, diazepam was found to have the ability, in a dose-dependent manner, to inhibit or reverse the stimulant effect of yohimbine. A correlation between the enhancing effect of yohimbine and the inhibiting effect of diazepam and the levels of monoamines and GABA in the brain was obtained. The role of central alpha2 adrenoceptors in controlling motor activity and neurotransnission was therefore confirmed.