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Abstract
20 middle aged patients with myasthenia gravis (MG) and 20 age, and sex matched controls underwent overnight polysomnography and neurophsychological test (p300 test), in order to test the hypothesis of SDB in MG and /or cognitive dysfunction and if their is relation between.
We observed in 55% of the myasthenics experienced apneas and /or hypopneas with resulting oxygen desaturations occurring during REM sleep and decrease of REM sleep .50% were hypopneas of central type of sleep apneas and 40% were apneas of central type however this is not associated with any cognitive impairment. No significant correlations between sleep parameters and cognitive parameters (clinically and
neurophysiologically).