الفهرس 
Introduction and Aim of the workOnly 14 pages are availabe for public view
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Abstract
Diabetes mellitus (DM) is a chronic that results from the body’s inability to sufficiently produce and/or properly use insulin. Insulin, a hormone secreted from beta cells in the pancreas, assists in the conversion of glucose into energy. Without insulin, the cells of the body, primarily in muscle, fat and liver tissue, cannot absorb sufficient glucose from the bloodstream. Consistent high levels of blood glucose can result in longterm damage, leading to the dysfunction and failure of various organs, such as the kidneys, eyes, nerves, heart and blood vessels. Complications in these organs can lead to death.
This study was conducted on a total of 120 subjects (40 females and 80 males). All patients were selected from the diabetes and endocrinology clinic at Beni-Sueif hospital. Subjects were divided into three groups:
A) GroupI: It is composed of 40 healthy subjects (females and males) of matching age to diabetic patients with a mean value of 45±7.
B) group II: It is composed of 40 patients (females and males) suffering from type II diabetes mellitus with poor glycemic control (i.e. uncontrolled). Their ages from 46 to 62 years with a mean value of 53.1 ± 6.2 years.
C) group III: It is consisted of 40 patients (females and males) suffering from type II diabetes mellitus and they were under glycemic control. Their ages ranged between 47 and 67 years with a mean value of 57.4 ± 7.2 years.
The following biochemical determinations were carried:- glucose (fasting and postprandial), fructosamine, glycated hemoglobin, total cholesterol, triglyceride, HDL-C, LDL-C and lipoprotein (a).
The following results were obtained:
(1) Significant increase in the level of serum fasting blood glucose, postprandial, glycated hemoglobin and fructosamine in uncontrolled group compared with controlled diabetics.
(2) Significant decrease in the serum concentration of cholesterol and LDL-C, but a non significant changes in the levels of LP (a) and triglycerides between uncontrolled and controlled diabetic patients.
(3) The following correlations were reported:
A) IN HEALTHY CONTROL:
• Fasting blood sugar vs. Total cholesterol
• Fasting blood sugar vs. LDL-C
• postprandial blood sugar vs. HDL-C
• Total cholesterol vs. triglyceride
• Total cholesterol vs. LDL-C
• Triglyceride vs. HDL-C
• HDL-C vs. LDL-C
B) IN UNCONTROLLED DIABETICS
• Glycated hemoglobin vs. fructosamine
• Fasting blood sugar vs. glycated hemoglobin
• Glycated hemoglobin vs. Triglyceride
• Glycated hemoglobin vs. LDL-C
• Total cholesterol vs. LDL-C
C) IN CONTROLLED DIABETICS
• Fasting blood sugar vs. glycated hemoglobin
• Glycated hemoglobin vs. Total cholesterol
• Glycated hemoglobin vs. LDL-C
• Total cholesterol vs. Triglyceride
• Total cholesterol vs. LDL-C
• Triglyceride vs. LDL -C
D) CORRELATION BETWEEN LIPOPROTEIN (A) AND OTHER VARIABLES IN HEALTHY SUBJECTS.
• Lp (a) vs. total cholesterol
E) CORRELATION BETWEEN LIPOPROTEIN (A) OTHER VARIABLES IN UNCONTROLLED SUBJECTS.
• No correlation was found
F) CORRELATION BETWEEN LIPOPROTEIN (A) AND OTHER VARIABLES IN CONTROLLED SUBJECTS.
• Lp (a) vs. HDL-C
G) CORRELATION BETWEEN LIPOPROTEIN (A) IN HEALTHY, UNCONTROLLED, AND CONTROLLED SUBJECTS.
• Correlation between healthy and controlled subjects only were reported.