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Abstract
Aim Of The Work This Study Aims To Evaluate The Activity Of Some B-Laclctam Antibiotics Which Are Communally Used In Clinical Field Against Some Pathogenic Bacteria Isolated from Different Sources (Wound, Respiratory Tract Infections And Urinary Tract Infections). Antibiotic Resistant Bacteria These Sources Are Important And Cause Serious Problem In Clinical Field.The Preesent Study Was Undertaken To Investigate The :Following Topics 1-Isolatipon And Purification Of Pathogenic Bacteria Different Sources.2- Studying The Susceptibillity And Resistance Of Bacterial Isolates from Patients To Different Antibioties.3- Identification Of-Resistant Isotates.4- Determination Of MiCs And MBCs Of Some B-Lactam Antibiotics Against Multi-Resistant Strains.5- Determination Of The B-Lactamase Activity Of Selected Multi-Resistant Strains.6- Studying Some Factors Affecting The B-Lactamase Activity By The Selected Strains.7- Molecular Studies Involved Protein Pattern And Plasmid Analysis.8- Effect Of Some Crude Oils Of Some Plants On The Growth Of Multi-Resisant Strains As Well AS Detemination Of MICs Of Thyme Oil Against Multi-Restant Strains.9-Effect Of Combination Between ThymeOil And B-lactam Antibiotics (Cefotaxime. Ampicillin) Each Separately On The Growth Of Multi-Resistant Strains Were Investigated.