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Abstract
The mesenteric small intestine is a difficult organ to examine. Long-term experience has shown that there are no shortcuts in achieving a reliable examination and several parameters need to be respected if a confident diagnosis is to be made. These would include selection of patients, closely supervised studies, background data, image quality, familiarity with imaging findings and utilization of radiologic–pathologic correlations. Thoughtful selection of patients by clinicians is essential to make radiologic examination cost effective. Closed supervised studies, incorporating an adequate index of clinical suspicion, cooperation between a focused radiologist and a keen physician, expertise and time are important. Familiarity with imaging findings and image quality, to guarantee demonstration of fine surface mucosal detail and transitional morphological changes are necessary. Applying the principles of radiologic–pathologic correlation to the interpretation of radiological findings offers a certain advantage and in association with the background data available, including localization and distribution of changes, extent of involvement, the solitary or multiple nature of the lesions present and the clinical history, provide a confident differential diagnosis.