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Abstract S U M M A R y In this investigation, FMD virus isolated from wild rots (0/rat strain) ,showed lower virulence for cattle end sheep, than the locally isolated virus (Oi/2/72) from cattle in spike of the identity of antigenic relationship of both strains. Experimentally infected cattle end sheep by FMD virus (O/rst strain) showed milder clinical signs then animals infected by Oi/2/72 strain of FMD virus. Serum neutralizing antibody titres of cattle and sheep infected by 0/ret strain were lower then animals infected by 0i/2/72 strain of FMD virus. Virus isolated from blood of cattle and sheep infected by 0/ret strain vas of lawer in titre then animals infected by 01/2/72 strain of FMD virus. Study the antigenic relationship revealed that 0/rot strain vas antigenically related to Oi/2/72 strain of FMD virus, although 01/2/72 strain of FMT) wo dominating the 0/rat strain. |