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Abstract 1-Introduction.2-Aim of the work :To predict endometrial hyperplasia in cases of PCOS, using clinical and transvaginal ultrasound criteria. 3-Review : A-Polycystic ovary syndrome (PCOS) : in this chapter the definition, Epidemiology, pathophysiology, pathology diagnosis of PCOS were discussed in details. B- Endometrial hyperplasia : Definition, classification and pathology were discussed. C- Transvaginal ultrasound (TVU) predictor of endometrial hyperplasia in PCOS. 4-Patients and methods : This study was conducted on a total of 60 women, with PCOS. Selection of Cases : Women of Reproductive age who had PCOS according to Rotterdam caitcria. Exclusion criteria : Presense of any other causes that mimic PCOS. Methods : Every women was sabjected to the following : I- Full history taking : With special careful for menstrual history. II- Complete examination : A) General : Obesity, waist circumference & waist/hip ratio, hirsutism, Acne and Acanthosis nigricans. B) Investigations for PCOS : 1- Biochemical : - Fasting blood sugure. -Fasting insulin. - Androgens : Testosterone, serum androstenedione and DHEAS. - Gonadotrophins : Lutenizing hormone & follicular stimulating hormone. - Estrogen : Estradiol (E2). 1- Transvaginal ultrasound : on day (22) of the menstrual cycle. I- Endometrial biopsy : Done as office procedure, on day (22) of menstrual cycle, immedietely after TVU, with novac connula. Then, the specimens were sent to the pathologist for histologic evaluation. 5-Results : The collected data were tabulated and analysed by using the suitable statistical methods. 6-Discussion : Different results and comparison with other studies were discussed. 7-Summary & Conclusion. 8-References. 9-Arabic Summary. |