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Abstract
Antibiotic resistance is a serious clinical problem in ICUs. Acquisition of resistance genes by Gram-negative bacteria is facilitated by mobile genetic elements called integrons, which are associated with resistance plasmids and transposons.
The present study was designed to study the prevalence of class I integron among Enterobacteriaceae spp. and Pseudomonas aeruginosa isolated from patients with UTIs and/or LRTIs in 5 ICUs in ASUHs and to determine the association between integron presence and MDR among the studied organisms.