الفهرس 
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Abstract
A total of 310 animal samples including 50 fecal (DROPping of broiler chicken) 260 intestinal content (105 broiler chicken, 50 cattle, 55 buffalo and 50 sheep) and 48 human fecal samples were collected from the investigated food animal contacts from El- Monieb and El-warak abattoirs and different animal and poultry farms at Giza Governorate. Bacteriological examination of samples revealed that 17 samples (10.96%) including 5 (10%) and 12 (11.42%) from poultry fecal DROPpings and intestinal content samples, respectively and 8(16.66%) out of the 48 human fecal samples were positive for Campylobacter. All the human and poultry Campylobacter isolates were biochemically identified to be C. jejuni and then were tested for their antibiotic susceptibility by agar disc diffusion method and the results showed that poultry Campylobacter strains displaying resistance of 64.71 % to ampicillin, streptomycin and cholarmphenicol and 58.82% to erythromycin and tetracycline. While, human strains resistance pattern was 87.5% to ampicillin, 75% to streptomycin and tetracycline, 62.5% to erythromycin and
50 % to cholarmphenicol. Regarding Salmonella; poultry (12.25%), cattle Cl 0%) and buffalo (10.9%) samples were positive Serological identification of the 30 animal and poultry Salmonella isolates revealed that 12 (40%) and 18(60%) of them were S. kentucky and S. enteritidis, respectively. 12 out of the human fecal samples (25%) gave culture for salmonellae and their serological identification revealed that 8 (66.7%) and 4 (33.3%) strains were S. enteritidis and S. kentucky, respectively. The resistance pattern of bovine (cattle & buffalo) Salmonella strains was 60 & 100, 80 & 66.7, 60 & 66.7, 60 50, and 40 & 50% to nalidixic acid, cephalothin, ampicillin, trimethoprime\ sulphamethoxazole and gentamycin, respectively. While, the poultry Salmonella strains showed resistance of 84.2% to gentamycin,73.6% to cephalothin, nalidixic acid and tetracycline, 68.4% to ofloxacin, cefoxitin and trimethoprime\ sulphamethoxazole, 57.8% to ampicillin and 52.6% to ciprofloxacin. Regarding human Salmonella strains, they showed resistance of 91.7% to cephalothin,75% to trimethoprime \ sulphamethoxazole and ampicillin, 50% to cefoxitin and 33.3% to cholramphenicol and gentamycin. It is recommended that control measures for decreasing antibiotic resistant in both Campylobacter and Salmonella species.