الفهرس 
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Abstract
The study was carried out on 600 marine fish of six different species that were represented as; Epinephelus tuvina, Siganus rivulatus, and Mugile sahlai native to Seuz-gulf at Seuz governorate; Tilapia spp, Mugile capito and Solea vulgaris native to Lake Quarn at El-Fayoum governorate, through the different seasons of the year 2006. The clinicopathological picture of the diseased fish was recorded. 245 fish were found to be infected with different types of bacterial species, of which, (203) fish were infected with Gram-negative bacteria and (42) fish were infected with Gram-positive one. (17.55%) of infected fish were positive for V. anguillarum, (16.73%) for V. alginolyticus, (15.51%) for P. piscicida, (15.91%) for Ps. fluorescens, (13.46%) for S. fecalis, (11.02%) for A. hyDROPhila, (6.12%) for A . sobria and (3.67%) were infected with Staph. aureus. Siganus rivulatus was the most infected fish spp (50%), followed by Epinephelus tuvina (42 %), Solea vulgaris (41 %), Tilapia spp. (40%), Mugile sahlai (38 %), while Mugile capito was the lowest infected one (34 %). The highest total prevalence of bacterial infection was recorded in summer season (40.81%) while the lowest one was recorded in winter (15.91%). Experimental infection with the different bacterial isolates caused nearly the same clinicopathological picture noticed in naturally infected fish.