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العنوان
Preparation of an improved inactivated H5N2 Avian influenza vaccine /
المؤلف
Mohamed, Hanan Sayed Abd Elgawad.
هيئة الاعداد
باحث / Hanan Sayed Abd Elgawad Mohamed
مشرف / Ahmed Abd El Ghani Elsanousi
مشرف / Hussin Ali Hussin
مشرف / Nadia Mohamed Ibrahim
الموضوع
Avian. Influenza vaccine.
تاريخ النشر
2010.
عدد الصفحات
124 Leaves :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
البيطري
تاريخ الإجازة
1/1/2010
مكان الإجازة
جامعة القاهرة - كلية الطب البيطري - Virology
الفهرس
Only 14 pages are availabe for public view

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from 166

Abstract

Preparation of inactivated H5N2 AI vaccine by using two types of inactivator BEl at
final cone. 0.003 MollL for 12 hours and heat 56°C for 240 mint and by using two
types of montanide adjuvant ISA 70 VG, ISA 763A VG. The four prepared vaccines
were used in vaccination of layer commercial chickens, in comparison with chickens
vaccinated by the imported vaccine. The humoral immunity was measured by HI test
and CMI was measured by lymphocyte proliferation and macrophage activity test. All
prepared vaccines reached the peak HI at the fourth week PV and the imported
vaccine reached the HI peak at the third week PV. The prepared vaccine by binary
inactivator with montanide ISA 763A VG higher HI titer than other prepared groups
at the fourth week PV and equal to the HI titer of imported vaccine (9.6 log, ), follow
them the group vaccinated by heat inactivated virus with montanide ISA 763A VG (9
log-). Results revealed that binary inactivated virus with montaninde ISA 763A VG
gives higher HI titer.