الفهرس 
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Abstract
Some toxicological and pharmacological studies were carried out on
Artemisia judaica; which is commonly used in folk medicine in Egypt. LD50 of
the ethanolic extract was 9.17 glkg b.wt., while the aqueous extract caused no
mortalities in mice till 5 g/kg b.wt. in mice. Both extracts showed significant
anti-inflammatory and analgesic effects, but didn’t show antipyretic effect. The
plant extracts showed no significant effect on urine output and had .no effect on
the blood pressure or pulse rate of normal rats. Moreover, the effect on blood
glucose level was determined in normal and diabetic rats. The results showed
that the plant extracts had significant lowering effect on the blood sugar level
of diabetic animals, but had no effect on blood glucose of normal animals. Both
extracts showed significant hepatoprotective effect on the intoxicated liver
using CCl4 in rats. In addition; the ethanolic extract showed significant
antioxidant activity in vitro, which was more prominent than that of the
aqueous extract. Prolonged administration of the plant extracts for two months
showed no adverse effect on blood picture, but there were slight changes in the
serum biochemical parameters, with observed decrease in body weight gain of
the treated groups when compared to control group. The plant extracts showed
inhibitory activity in the isolated rabbit intestine, and their action was similar to
that of nicotine. They also showed varying inhibitory effect on the uterine
motility of rats at different stages of estrus cycle.