الفهرس | Only 14 pages are availabe for public view |
Abstract Cervical cancer is one of the leading causes of cancer related deaths in developing countries worldwide with incidence rates varying considerably from 3 to 61 per 100.000 females. In western world cervical cancer screening has been shown to decrease the incidence of invasive cervical cancer rates and decrease cervical cancer related mortality through the cytology based screening programs. Our study included 5000 women. Cervical smears were obtained from all women for cytolgoic evaluation followed by visual inspection of cervix after acetic acid application (VIA) women with positive report on either test were reffered for colposcopy and biopsy when appropriate in order to decrease the verification bias all women were subjected to both screening tests, all women attended Minofeia University outpatient clinic were referred for colposcopy also colposcopy was performed for women with negative VIA and negative smears if they had contact bleeding, chronic per vaginal discharge or grossly looking unhealthy cervix. Results of VIA were normal in 4850 women (97%) and showed abnormal acetowhite appearance in 150 (3%) women. There were 2089 (41.78%) colposcopic examinations and 200 biopsies (4%) were carried out, picking up 50 cases of premalignant lesions (1%). Premalignant lesions were 47 LSIL and 3 HSIL. VIA detected 48 of the 50 premalignant lesions (sensitivity 96%, specificity 97.5%, PPV 50%) VIA missed 2 cases of LSIL. |