الفهرس 
mechanism of phhalate toxicity on reproductionOnly 14 pages are availabe for public view
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Abstract
The present study investigated the efficacy of ginseng to attenuate
DBP-induced male infertility, hormonal disorders, oxidative damage
and testicular dysfunction in adult male rats. A total of 40 male
albino rats were divided into four groups (10 rats each). The first
group served as control and received corn oil only (5 ml/kg body
weight). Rats of the second group received DBP at the dose of 500
mg/kg body weight/day by oral gavage. Rats of the third group
received ginseng root extract at a dose of 100 mg/kg body weight/
day while rats of the fourth group received both DBP and ginseng
with the same mentioned doses and route of administration, for ten
successive weeks, the duration of the experiment. Results showed
that, DBP treatment induced male infertility via decrease testis,
epidydmis, prostate and seminal vesicle relative weights, these effects
associated with decline in sperm count and motility and elevation in
dead and abnormal sperm morphology percentages. Moreover, DBP
lead to hormonal disorders that reported as decline in serum
testosterone, estradiol, progesterone, triiodothyronine and thyroxine
with a concomitant increase in serum follicle stimulating hormone,
luteinizing hormone and thyroid stimulating hormone.