الفهرس | Only 14 pages are availabe for public view |
Abstract In diabetes mellitus, which is one of the leading health problems all over the world, there is an increased susceptibility to infections. Skin infections are extremely frequent in the diabetics, either as a complication during the course of the disease, or appear early at its onset. This study was a trial to isolate and identify the different micro-organisms present in ulcerated or infect ad skin lesions in 60 ’diabetic patients, from 5 different . hospitals and diabetic clinics, and. to test their sensi tivity to different antibiotics by disc diffusion method. ., It was found that: . - Out of.the studied 60 diabetic patients, 61.7 were males and 38.3 were females, and skin infections were most frequent at the age group 60 - 69, followed by 5~ - 59 years in both sexes. - A positive correlation was found between the duration of the illness and the presence of skin complications. - Skin infections were more common among diabetics who were treated with oral hypoglycemics, than those under insulin therapy. - The foot was the most common site of skin infections. . - The number of the Gra.m. -positive and Gram-negative isolates was nearly similar. - Staphylococci were the most frequent 1y isolated organisms. Staph.aureus was isolated from 33.3 of the p~tients, out of which 18.7 were in pure culture. Proteus species was also iso1a.ted from 33.3 of the patients, 6.6 out of them were in pure culture. ~.co1~ was isolated from 21.6, Pseudomonas species from 20 and Klebsiella species from 13.3 of the patients. Most of the Gram-positive isolates were highly suscep. tible to gentamicine (84.5) and rifampicin (77~6). These were followed by cloxacillin (32.7), amoxaci llin and ampicillin (29.3) each. Most of the isolates were resistant to penicillin, streptomycin and tetracycline. - Also the Gram-negative isolates were sensitive to gen tamicine (84.7), followed by rifampicin (45.7). Recommendations: - Metioulous oare of the skin o~ the diabetio patients is absolutely necessary, specially the feet. - Good diabetio oontrol is important to prevent skin infections, specially for those who are treated with oral hypoglycemics. - In case of skin infections, cultures should always be done. Antibiotics should be selected (for treat ment) aocording to the results of the sensitivity tests, since most of the organisms are becoming re I sistant to most o~ the commonly used antibiotics. |