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العنوان
Molecular biological and biochemical syudies on gene expression of aging /
المؤلف
Ahmed, Shimaa El-said abd allah.
هيئة الاعداد
باحث / شيماء السعيد عبدالله احمد
مشرف / يوسف محمد شحاته
مشرف / محمد اسماعيل محمد اسماعيل
مشرف / محمد اسماعيل محمد اسماعيل
الموضوع
Veterinary clinical biochemistry.
تاريخ النشر
2011.
عدد الصفحات
92 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
البيطري
تاريخ الإجازة
1/1/2011
مكان الإجازة
جامعة الزقازيق - كلية الطب البيطرى - Biochemistry
الفهرس
Only 14 pages are availabe for public view

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Abstract

As a result, of the great deal of attention and interest which
has been directed toward the study of aging and possible roleof
antioxidants.
This work was designed to throw further light on the possible
scavenger effect of three naturally occurring products, Garlic,
Ginseng and Melatonin in adult and aged rats.
The present study deals with the following parameters as:
1- Hepatic reduced glutathione.
2- Hepatic glutathione peroxidase (GSH-px).
3- Hepatic superoxide dismutaese (SOD).
4- Hepatic catalase (CAT).
5- Glucose-6- phosphate dehydrogenase (G-6-ph-D).
6- Hepatic malondaldehyde (MDA).
7 - Gene expression of glucose-o-phosphate dehydrogenase.
A total of rats where used in the present study divided into two
groups:
1- Adult rats (6 months).
II-Aged rats (14 months).
Each group subdivided into 4 groups:
1- Control group (received normal food only).
2- Melatonin group (received Melatonin).
3- Garlic group (received garlic) with normal food.
4- Ginseng group (received ginseng) with normal food.
The obtained results showed that:
l-Hepatic glutathione peroxidase:
There is increased in the activity of glutathione peroxidase
in aged and adults rats compared with control group.