الفهرس 
Chronic liver diseasesOnly 14 pages are availabe for public view
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Abstract
Hyaluronic acid (HA) is a naturally occurring high molecular weight polysaccharide produced mainly by fibroblast and other specialized connective tissue cells in the body. HA is cleared in the liver by very efficient and specific receptor mechanism in sinusoidal endothelial cells The aim of this study was to assess the relationship between HA level in blood and chronic liver diseases This study included 55 patients 38 males and 25 females, their ages ranged between 17-64 years, in addition to 20 apparently healthy subjects age and gender matched as a control group, 12 males and 8females, with age ranged between 38-50 years. The studied subjects were divided into 3 groups, group Ia included 10 chronic HCV patients without liver cirrhosis (with different degrees of fibrosis they were 8 males and 2 females with age ranged between 37-51 years, group Ib included 15 chronic HCV patients with liver cirrhosis they were 9 males and 6 females with age ranged between 45-63years, group Ic included 10 chronic HBV patients they were 9 males and 1 females with age ranged between 17-40 years. Group II included 20 HCC patients, they were 12 males and 8 females with age ranged between 50-64 years and group III included 20 apparently healthy subjects as a control group they were 12 males and 8 females with age ranged between 38-50 years Patients and control group were submitted to thorough history taking, clinical examination, abdominal ultrasonography, liver function tests, and estimation of serum HA level.