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العنوان
Design, Synthesis and Biological Evaluation of a
New Series of Nucleosides and Their
Intercalation with DNA
المؤلف
Osman, Amany Mostafa Ahmed .
هيئة الاعداد
باحث / Amany Mostafa Ahmed Osman
مشرف / Erik B. Pedersen
مشرف / Hamed M. Abdel-Bary
مشرف / Adel A.-H. Nassar
الموضوع
الكيمياء العضوية
تاريخ النشر
2008.
عدد الصفحات
700 mg :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
Organic Chemistry
تاريخ الإجازة
1/1/2008
مكان الإجازة
اتحاد مكتبات الجامعات المصرية - Chemistry
الفهرس
Only 14 pages are availabe for public view

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Abstract

In this Thesis two projects are presented. The first project described the synthesis of an aryl
phenanthroimidazole moiety as a conjugated flexible intercalator to improve the hybridization
efficiency of a triplex forming oligonucleotide. The second project described the synthesis of
Twisted Intercalating Nucleic Acids (TINA analogue) with High Physiological Thermal Triplex.