الفهرس 
Basic process of gene therapyOnly 14 pages are availabe for public view
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Abstract
Major advances in our current perception of how cancers may develop have led to the consideration of cancer as a genetic disease resulting in the abnormal proliferation of a clone of cells. Carcinogenesis appears to be a multistep process in which a series of genetic alterations occur within one cell, leading to malignancy.
The advent of recombinant DNA technology has sparked the age of molecular medicine. The ability to deliberately recombine pieces of DNA and then transfer these specific genes into diseased cells has revolutionized medical research. In fact, the ability to modify these genes in the living person is now possible. Several innovative approaches are being developed to circumvent the limitations of current vectors including more effective delivery routes for gene therapy, Gene therapy strategies are rapidly evolving as new gene targets, better vectors and improved gene expression systems become available. Innovative gene therapy strategies currently being employed for the treatment of urological tumors include: immunotherapy, gene corrective therapy, exploitation of programmed cell death therapy, gene therapy to target critical biological functions of the cell, suicide gene therapy, oncolytic virus gene therapy, and finally combination gene therapy. Overall, current gene therapy to treat urological tumors has been shown to be safe and feasible.