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Abstract Acute coronary syndrome remains the leading cause of morbidity and mortality worldwide .It describes aspectrum of clinical syndromes ranging from unstable angina(UA) and non-ST-elevation myocardial infarction(NSTEMI) to ST-segment elevation myocardial infarction (STEMI). In this context, NSTEMI is distinguished from UA by the presence of elevated serum level of cardiac biomarkers. Non-ST-elevation myocardial infarction have a higher late mortality (8.9% at 6 month) compared with ST-elevation myocardial infarction(6.8% at 6 month). Non-ST-segment elevation acute coronary syndrome(NSTE-ACS) due to left main coronary artery disease or three vessel disease thrombosis is a catastrophic event associated with poor prognosis and high in hospital mortality. Early recognition and emergent revasularization is vital for survival. An early identification of patients with left main and/or three vessel disease is an important factor in the prognosis and selection of the optimal treatment strategy in patients with NSTE-ACS. The aim of this work to compare the clinical variables of patients with left main and/or three vessel disease on admission with those of patients without it to derive an early simple predictor of left main and/or three vessel disease in patients with NSTEMI. This study included fifty patients presented with NSTE-ACS underwent cardiac catheterization for coronary angiography to diagnose and evaluate coronary artery disease, among the 50 Patients 34 were male (78%) and 16 were female (22 %). |