الفهرس 
Historical backgroundOnly 14 pages are availabe for public view
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Abstract
Background: Endoscopic procedures for ventricular lesions and for sella turcica are well established, while its use in skull base cisterns is still a matter of controversy. The aim of study is delineation of the role of neuroendoscopy in surgery of skull base and cisternal pathologies as regards additional benefits, visual aid, exploring hidden surgical corridors, increasing extent of tumor removal and avoiding complications
Methods: This study included the implication of neuro endoscopy for skull base and cisternal pathologies in 45 cases managed at Mansoura university Hospitals Neurosurgery Department from May 2007 till June 2011. The results obtained from the present group were compared to results obtained from revision the medical records of 68 patients with skull base and cisternal pathologies managed at department of neurosurgery, Mansoura university archive during period between June 2005 and June 2007
Results: We managed 45 patients in the first prospective group while we revised files of 68 patients in the retrospective group. Total resection of tumours achieved in 58.3% of the prospective group versus 28.6% of retrospective group. Subtotal resection achieved 8.3% versus 50.8% . Near total resection in30.6% versus 14.3% in prospective and retrospective groups respectivly. The lesion was biopsied in 6.3% of retrospective versus 2.8% in prospective group. Complications occurred in 8 patients of prospective group accounting for 17.8% in comparison to 28 patients accounting for 41.2% of retrospective group (P value is <0.001).
Conclusion: Endoscopic assisted microsurgical approaches led to better outcome and decreased the incidence of complications. Endoscopic Endonasal transphenoid approach is superior to microscopic approach with superior outcome and better complication rates.