الفهرس 
DIABETES MELLITUSOnly 14 pages are availabe for public view
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Abstract
The aims of this study were to compare the glycemic and the peak incremental indices of honey and sucrose and to compare the effects of each of honey, sucrose and glucose on the C-peptide level in children and adolescents with type 1 diabetes mellitus and in non diabetics.
Our study was a case control cross-sectional study which was conducted on 20 children and adolescents suffering from type 1diabetes mellitus and 10 healthy non diabetic children and adolescents serving as controls. The patients were recruited from the regular attendants of the children clinic of the National Institute of Diabetes of Cairo. Their mean age was 11.30 yr and they were10 males and 10 females.
All patients were subjected to: 1) a structured questionnaire to fulfill detailed illness history, 2) thorough clinical examination, 3) laboratory investigations including: a- Oral sugar tolerance tests using glucose, sucrose and honey in three separate sittings, b- Measurement of fasting and postprandial serum C-peptide levels 4) Calculations of the rate of C-peptide increase, the glycemic and the peak incremental indices and 5) Statistical analysis of obtained data.
And we found that there is:
1- No statistical significant differences between patients and controls as regards age and anthropometric measurements including percentage of weight to that at the 50% percentile for age (wt%) , percentage of height to that of the 50% percentile for age (ht%) and body mass index (BMI).
2- No statistical significant differences concerning the glycemic and the peak incremental indices (after ingestion of sucrose or honey) among patients and controls
3-A statistically significant lower GI and PII of honey compared to those of sucrose in patients.
4- Statistical significant lower glycemic and peak incremental indices after honey ingestion compared to those after sucrose ingestion in the control group.
5- A High statistical significant reduction in fasting and 2 hours postprandial C-peptide levels in patients compared to controls.
6- No statistical significant differences as regards the percentages of C-peptide level increase before and after glucose, sucrose or honey ingestion in the patients group.
7- Statistical significant higher percentages of C-peptide level increase following honey ingestion when compared to those following glucose or sucrose in the non diabetic controls.