الفهرس 
Liver CirrhosisOnly 14 pages are availabe for public view
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Abstract
Liver cirrhosis, which is the final stage of chronic
liver damage of various etiologies, results in major
complications such as portal hypertension, variceal
bleeding, ascites, spontaneous bacterial peritonitis,
hepatic encephalopathy and hepatorenal syndrome.
Spontaneous Bacterial Peritonitis is defined as an
infection of the previously sterile ascitic fluid in absence
of intraabdominal inflammatory focus.
The pathogenesis of SBP thought to be due to
intestinal bacterial overgrowth, the alterations (structural
and functional) of the intestinal mucosal barrier and the
deficiencies of the local immune response.
Complement system is one of the major immune
defense systems of the body. The proteins of the
complement cascade have been found in peritoneal
fluid, with lower levels in cirrhotic patients than in
patients with ascites of other etiologies. The ascetic fluid
Complement 3 is an important factor to offer local
defense against infection of ascetic fluid.