![]() | Only 14 pages are availabe for public view |
Abstract The association between microalbuminuria and hypertension was described a long time ago. Both microalbuminuria and left ventricular hypertrophy may reflect target organ damage. We studied the prevalence of left ventricular hypertrophy in ٦٠ hypertensive non diabetic patients, with microalbuminuria at the period from December ٢٠٠٣ to August ٢٠٠٤. We found that ٦٥% of all the patients had left ventricular hypertrophy, and ٥% had renal parynchematus disease. Microalbuminuria, defined as a urinary albumin excretion between ٣٠-٣٠٠ mg/٢٤ hours, was a strong predictor of left ventricular hypertrophy. For ١٢ weeks, ٣٠ patients were treated by ACE inhibitors (group A) and the rest of the patients (group B) were treated by other antihypertensive modalities. We found that group (A) showed significant DROP in the level of microalbuminuria and hence the degree of left ventricular hypertrophy, with no changes in the kidney function, in comparison to group (B). So ACE inhibitors show their ability to control microalbuminuria and decrease level of left ventricular hypertrophy, without affectation of the kidney function, in comparison to other antihypertensive drugs. Key words: hypertension, microalbuminuria, left ventricular hypertrophy, ACE inhibitors. |