الفهرس 
PROPOFOLOnly 14 pages are availabe for public view
 |  | from | 130 |  |  |
| | | from | 130 | | |
Abstract
The availability of ultra short acting intravenous anesthetic drugs like propofol and remifentanil with potent anti-emetic characteristics for the first and analgesic characteristics for the second has enabled more surgical procedures to be done on an outpatient basis. The pharmacokinetics of remifentanil allow easy titration for changing intra operative conditions and predictable emergence from anesthesia. A total intravenous anesthesia (TIVA) regimen with remifentanil and propofol is a useful anesthetic technique, effectively controlling responses to tracheal intubation and intense surgical stimulation, while allowing for rapid emergence from anesthesia without prolonged respiratory depression.The availability of less soluble inhalation anesthetics such as sevoflurane has led to reassessment of the use of volatile anesthetics for out patients surgical procedures. Given the low blood-gas partition coefficient of sevoflurane (0.69), a more rapid elimination is seen. Studies on sevoflurane reported to have shorter emergence times compared to isoflurane-based techniques.The aim of this study was to compare total intravenous anesthesia using remifentanil with propofol and balanced inhalation anesthesia using sevoflurane and fentanyl as regard hemodynamics, recovery profiles, postoperative side effects, total analgesic consumption postoperatively, stress response and pulmonary function tests.Sixty patients of both sexes, physical status I or II, aged 22 – 55 years, scheduled for elective Laporoscopic cholecystectomy and studied were prospectively.
They were receive either total intravenous anesthesia (TIVA) with propofol and Remifentanil (30 patients) or inhalational anesthesia with sevoflurane and fentanyl (30 patients) paracetamol 1000 mg was administered intravenously 15 min before anesthesia as a pre-emptive analgesic.