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Abstract Results of this study revealed that moxifloxacin and terbinafine antimicrobial drugs caused a teratogenic effect and dereased male fertility in Sprague - Dawley rats . Both drugs induced dose - dependent decrease in mothers body weight gain , placental weight , caused abortion in some pregnant female , early fetal resortions and fetal deaths as well as growth retardation in some fetuses obtained from pregnant rats given these drugs during the period of organogenesis. |