الفهرس 
HYPERTENSIONOnly 14 pages are availabe for public view
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Abstract
H
ypertension is a major cardiovascular risk. Of all known risk factors, hypertension is the most prevalent.
Arterial systemic hypertension due to increased overload results in changes in left ventricular remodeling and left ventricular hypertrophy, beside well known impairment of both diastolic and systolic function.
Left ventricular hypertrophy is the most powerful risk factor for coronary heart disease, ventricular arrhythmias, congestive heart failure and sudden death.
It is well known that many cardiac diseases affect both the left ventricles and the right ventricles; and that left ventricular failure may secondary impair right ventricular diastolic performance, through elevation of the pulmonary artery pressure or ventricular interdependence.
This study aimed to determine the effect of hypertension on right ventricular systolic and diastolic function.
This study included two groups, group (I) that included 20 healthy individuals, and group (II) that included 30 hypertensive patients, whose blood pressure was not more than 140/90 mmHg and had no lung or heart disease.
Patients in the study were subjected to full history with special emphasis on age, gender, diabetes, duration of hypertension, duration of treatment and type of treatment. Clinical examination to exclude heart and lung disease.
2D echocardiography and Doppler examination was performed, LV dimensions were measured including LVEDD, LVESD and left ventricular ejection fraction, Pulsed-wave Doppler echocardiography was performed for measuring mitral and tricuspid inflow velocity. Tissue doppler imaging at the level of RV free wall basal side of tricuspid annulus and the following parameters were measured; systolic wave, early filling phase and late filling phase.
TAPSE, Strain and Strain Rate of RV, are also assessed.
Results of the current study showed that there was no significant difference between the two groups regarding age, height and weight but there was a significant statistical difference regarding the BMI of both groups (p value < 0.05).
Regarding LV echo parameters, the comparison between the two groups showed statistically no significant difference between them as regards EDD, ESD, IVD, EF%. But there was statistically significant difference between the two groups regarding Posterior Wall, ratio of flow across mitral valve (LV).
Regarding RV parameters, there was no statistically significant difference between the two groups regarding Peak E, E’, S’ and TAPSE (p value >0.05).
But There was statistically significant difference between the two groups regarding Peak A , ratio of flow across tricuspid valve (RV), A’, Strain and Strain Rate of RV (Pvalue <0.05).
So it was concluded that hypertensive patients, experienced RV diastolic impairment as evident by pulsed Doppler and tissue Doppler derived measures, also subtle disturbance in RV systolic contractility was evident.