الفهرس 
Introduction & Aim of the Work
Diabetes MellitusOnly 14 pages are availabe for public view
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Abstract
This study was carried out on 60 subjects divided into:
Group I: included 20 apparently healthy subjects (as control group).
Group II: included 20 patients with type 2 diabetes mellitus without renal impairment.
Group III: included 20 patients with diabetic nephropathy.
All patients and controls were subjected to the following investigations:
Routine investigations:
1. CBC and differential WBCs count.
2. Erythrocytes sedimentation rate (ESR).
3. Fasting& post-prandial blood glucose.
4. Glycated hemoglobin [HbA1c].
5. Renal function tests (blood urea, serum creatinine and serum uric acid).
6. Liver function tests (serum bilirubin, ALT, AST, serum albumin and total proteins).
7. Serum total cholesterol and serum triglycerides.
8. A/C ratio.
B) Special investigations:
9. Adiponectin level by Enzyme Immunoassay (EIA).
10. CD146 by Flowcytometry.
11. Microalbuminuria by Enzyme immunoassay (EIA).
Results of different groups were compared with each other and were summarized as follows:
There was a statistically significant elevation in urea (P-value =0.001), creatinine (P-value =0.001), uric acid (P-value = 0.001), Microalbumin (P-value = 0.001) and Adiponectin (P-value = 0.004, P-value=0.003) respectively,when comparing group I and II to group III.
There was statistically significant difference in CD146 percentage among group II when compared to both group I and group III (P-value = 0.001, P-value=0.004) respectively.
There was significant positive correlation between serum Adiponectin and the duration of the disease in group III (r = 0.45, P-value = 0.04), also, between CD146 and the duration of the disease in group III (r = 0.56, P-value = 0.01).