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العنوان
PREVALENCE OF INSULIN RESISTANCE SYNDROME AMONG CHILDREN AND ADOLESCENTS AND LIFESTYLE INTERVENTION FOR HIGH RISK GROUP
المؤلف
Hammad, Elsayed Mahmoud Elsayed.
هيئة الاعداد
باحث / Elsayed Mahmoud Elsayed Hammad Abou El-Ella
مشرف / Hamdia Ahmed Helal،
مناقش / Hamdia Ahmed Helal،
مناقش / Nebal Abd El-Rahman Abou El-Ella
الموضوع
nutrition. Insulin shock therapy. Diabetes. Children- Diseases.
تاريخ النشر
2012.
عدد الصفحات
1 computer optical disc ;
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
علوم المواد
تاريخ الإجازة
10/6/2012
مكان الإجازة
جامعة المنوفية - كلية الإقتصاد المنزلى - .Department Of Nutrition and Food Science
الفهرس
Only 14 pages are availabe for public view

from 226

from 226

Abstract

This study was carried out to revise the prevalence of nutrition disorders and abnormal laboratory findings like fasting blood glucose levels, lipid profile (total cholesterol; TC, and triglycerides; TG), lipoprotein patterns (low density lipoprotein LDL-c, and high density lipoprotein; HDL-c), and fasting plasma insulin among obese children and adolescents, to test the presence of insulin resistance syndrome among those with other disorders to clarify the association between obesity and physical inactivity and dietary practices , and to assess HOMA R as screening and monitoring test for insulin resistance syndrome among obese children and adolescents 100 obese children and adolescents (age from 6 - 18 years, mean age 11.610± 3.516 year) were assessed. Two main types of data were reported (medical and dietary) to cover topics related to obesity, diabetes, hypertension and physical activity. Weight height, waist and BMI were measured and referred to their corresponding international reference values properly matched for age and sex. A Fasting blood sample was drawn to assess lipid (total cholesterol; TC, and triglycerides; TG), lipoprotein patterns (low density lipoprotein; LDL-c, and high density lipoprotein; HDL-c), fasting blood glucose and fasting plasma insulin. HOMA-R was calculated using a computer-derived equation to assess body response to insulin among target br>Results
Main results of our study showed that 68 %from total sample
had HOMA-IR > 2.5 this mean that around tow-third from total sample were resistant to insulin with higher prevalence among females than males and higher prevalence among adolescents than children. This study also showed significant relation between insulin resistance syndrome and dietary pattern of the studied sample. Main results of our life style intervention showed very highly significant changes between pre and postanthropometric measurements for sub sample (n=32) from the total studied cases0.000 for both Weight (Kg), BMI)Kg/m2) and Waist Circumference (cm). These changes also
lead to laboratory improvement in insulin resistance syndromeindicators like fasting blood glucose levels, glycated
hemoglobin HbA1c %, lipid profile (total cholesterol; TC, and
triglycerides; TG), lipoprotein patterns (low density lipoproteinLDL-c, and high density lipoprotein; HDL-c), and fasting
plasma insulin among obese children and adolescents whomincluded with our intervention. This means that the healthy life
style intervention (by encouraging daily physical activities,
exercises with balanced low caloric diet and planning to reduce
about 10% from body weight) is very useful for preventing or
reducing insulin resistance syndrome and its complications
among obese children and adolescents.
Summary
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Diet and lifestyle modifications are the first line of
treatment in dealing with insulin resistance syndrome as the
main recommendations are to balance caloric intake and
physical activity to achieve and maintain a healthy body weight
as possible as.