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العنوان
Some studies on hydatidosis in camels /
المؤلف
El-Kattan, Adel Mahrous Abdel Maksoud.
هيئة الاعداد
باحث / عـادل محروس عبدالمقصود القطان
مشرف / رؤوف رزق يوســـــف
مشرف / محمـد عزت أنـورشوكت
مشرف / وحيد محمد على موسي
مشرف / طــارق رمضــان أبوالنـــجا
الموضوع
Camels. Hydatidosis. Epidemiology. Serodiagnosis. Antigens. Immunity.
تاريخ النشر
2012.
عدد الصفحات
169 leaves :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
البيطري
تاريخ الإجازة
1/1/2012
مكان الإجازة
جامعة القاهرة - كلية الطب البيطري - Infectious Diseases
الفهرس
Only 14 pages are availabe for public view

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Abstract

In the present study on hydatidosis in camels we firstly conduct an epidemiological study revealed that, the overall prevalence of hydatidosis was (17.61%) while it was (18.66%) and (11.53%) for male and female camels respectively. It was found that, the peak prevalence rate was during Summer (23.23%) while the lowest rate was during Winter (11.85%). Apparently and post mortem examination of camels revealed that, fair healthy and week animals were found to be infected by (16.62%) and (21.49%) respectively. Lung was the most predominant site of infection as, (94.62%) of infected camels had pulmonary cysts while (5.37%) were infected in the liver. (77.08%) of examined cysts were fertile, (65.6%) were fertile and viable, (4.16%) were calcified, (13.54%) caseated and (5.20%) were sterile. Medium sized cysts were the most prevalent in the infected lung (45.5%) while hepatic cysts were mostly of small size (66.6%).crude and partially purified cyst fluid antigens were evaluated in the serodiagnosis of camel hydatidosis revealing sensitivity (82.75% &79.31%) and specificity (62.5%, 75%) for crude and partially purified antigens respectively. Protein fractionation of both antigens revealed 10 and 9 bands respectively showing some relative and similar bands. After immunization with the previous hydatid fluid antigens and irradiated protoscolex Ag separately in different groups of lab. animals for induction of protective immunity, cellular and humeral immunity achieved was evaluated in addition to evaluation of the number, size, shape and load of the formed cysts in comparison with control group. The lymphocyte proliferation was increased in comparison with the control group and with that of 0 time specially after challenge. The antibody production was produced in a protective titer 2 weeks post immunization in case of the fluid Ags and after 6 weeks in the irradiated protoscoleces Ag reaching their peaks at (8-12) weeks then began to decrease after the 16th week post immunization. Cyst evaluation after slaughtering revealed (87.5%, 91.6% and 70.83%) protection degrees for crude Ag, partially purified Ag and irradiated protscolex Ag respectively with the formation of 3, 2 and 7 cysts respectively smaller in size than that of the control group. Another challenged group was used to evaluate the efficacy of treatment with albendazole revealed a degree of protection (75%) as out of 4 infected animals 3 were found harbor hydatid cysts (6 in number and smaller in size than that of the control group).